*Content reviewed by HotPause Health medical advisor, Bridget McCormick, LMFT

ADHD and Menopause: Midlife Brain Function Changes

If you’ve been blaming your brain fog on midlife and powering through with sticky notes, caffeine, and sheer willpower, you’re not alone. But if lack of focus, forgetfulness, or being overwhelmed start to feel like more than a passing phase, there might be more to the story.

For women with ADHD, or those who are only now realizing they may have it, perimenopause brings on a new perspective. This transition can elevate behavior to a level that’s hard to ignore. The hormonal rollercoaster of midlife doesn’t just impact your cycles, sleep, and moods. It can also shake up your brain’s ability to function the way it used to.

Let’s break it down.

What is ADHD?

ADHD (Attention-Deficit/Hyperactivity Disorder) is a neurodevelopmental condition that affects attention, impulsivity, and organization. It’s increasingly being recognized in adult women, many of whom were overlooked in childhood because their symptoms didn’t fit the classic mold and it was traditionally thought to primarily affect boys.

For some women, ADHD looks like:

• Losing track of tasks
• Difficulty concentrating
• Struggling to stay organized
• Feeling mentally restless
• Frequently forgetting appointments, names, or where you left your keys
• Hyperactivity and/or impulsivity

Hormones, ADHD, and the Midlife Connection

Scientists have known for years that dopamine, the “pay-attention” neurotransmitter that tends to run low in ADHD, is linked to estrogen. When estrogen climbs, dopamine signaling usually sharpens. When estrogen drops, dopamine can sputter. Therefore, any serious hormonal roller-coaster has the power to yank ADHD symptoms along for the ride.

Early, but compelling research suggests women with ADHD feel these hormonal tremors more acutely than their neurotypical peers:

• Women diagnosed with ADHD are roughly five times more likely to develop post-partum depression or anxiety than mothers without ADHD.
• When starting a combined oral contraceptive, they have a higher risk of depression.
• During the late-cycle luteal phase, they report increased PMS symptoms and are more likely to meet criteria for PMDD.
  

Fast-forward to midlife and the pattern continues. Many women share that their brain fog, distractibility, and emotional snap-points spike during perimenopause and early menopause. This is precisely the time when estrogen levels begin to look like the “zone of chaos” – imagine a seismograph rather than a calm tide chart. Small clinical studies echo these lived-experiences, hinting that ADHD symptoms do intensify as hormones fluctuate.

It isn’t crystal clear yet whether estrogen itself is driving that surge, or whether classic menopause burdens like night sweats, disrupted sleep, joint pain, “Where-did-I-put-my-phone?” moments simply make ADHD harder to wrangle. Realistically, both forces are probably in play. What is certain: if you already navigate life with ADHD, the following are imperative – supporting hormonal health, prioritizing sleep, incorporating stress management, incorporating healthy nutrition and committing to exercise/fitness.

The science isn’t settled yet, but attention is finally being paid to how ADHD presents in midlife women. It’s long-overdue, but a positive step forward.

What You Can Do About ADHD in Menopause

If you’re struggling with memory, focus, or executive function, it’s worth exploring whether ADHD could be part of the picture. It’s especially important if these symptoms are interfering with daily life.

Here’s where to start:

• Talk to a healthcare provider who understands both menopause and neurodiversity
• Track your symptoms and how they relate to your cycle (if you still have one)
• Although there is no cure for ADHD, there are behavioral strategies, medication and hormone therapies that can improve your quality of life. 

The Bottom Line

You don’t have to accept cognitive decline as a “normal” part of menopause, especially if it’s making your daily life harder than it needs to be. Whether it’s ADHD, hormone shifts, or both, your experience is valid, and there’s help available. We’re just beginning to understand how ADHD and menopause intersect, but the message is clear: if your brain feels like it’s betraying you, you deserve answers and support.